Pathophysiological aspects
Up one level Adiponectin: a new "hot" marker of the Metabolic Syndrome2009
- 12/23 - Strong association of metabolic syndrome with vascular dysfunction and low-grade inflammation in nondiabetic Japanese subjects
- 12/16 - Serum apolipoprotein C-III in high-density lipoproteins as key diabetogenic risk factor in Turks
- 12/01 - Type 2 diabetes and elevated triglycerides linked to HIV-associated sensory neuropathy
- 11/30 - Elevated carotid intima-media thickness and intra-renal resistance at an early stage of metabolic syndrome
- 11/19 - Metabolic syndrome as a risk factor influencing long-term survival in peritoneal dialysis patients
- 11/13 - Metabolic syndrome as an independent risk factor for increased arterial stiffness in Japanese subjects
- 11/09 - Metabolic syndrome after renal transplantation: a prominent risk factor for graft failure
- 11/06 - Increased ventricular arrhythmogenicity in metabolic syndrome is associated with myocardial dysfunction, risk factors for atherosclerosis, and low-grade inflammation
- 10/30 - Sleep disordered breathing as an integral part of metabolic syndrome
- 10/05 - Predictors of increased risk of carotid plaque rupture and thrombosis
- 09/24 - Visceral fat-dominant accumulation associated with hepatic insulin resistance in men with type 2 diabetes
- 09/17 - Children with nonalcoholic fatty liver may develop end-stage liver disease
- 09/14 - Early detection and prevention of chronic kidney disease in nondiabetic, nonhypertensive adults with metabolic syndrome
- 09/03 - Age-related variation in systemic inflammatory markers largely explained by differences in visceral adipose tissue
- 08/27 - Metabolic syndrome is associated with increased aortic pulse pressure and ascending aortic pulsatility in patients with normal coronary arteries
- 08/21 - Prevalence of nonalcoholic fatty liver in children and adolescents closely related to metabolic syndrome, insulin resistance, and waist circumference
- 08/10 - Inflammatory mediators in morbidly obese subjects associated with glucose homeostasis abnormalities
- 08/07 - Lower urinary tract symptoms linked to metabolic syndrome in men
- 08/04 - Sympathetic overactivity not uniformly distributed over the cardiovascular system in metabolic syndrome
- 08/03 - Relationships between blood pressure and left ventricular mass index are influenced by excess adiposity
- 07/31 - Coronary endothelial dysfunction is positively related to low-density lipoprotein and inversely related to high-density lipoprotein subclass particles
- 07/30 - Metabolic syndrome associated with impaired left ventricular synchronicity
- 07/29 - Metabolic syndrome impacts on the increase in high sensitivity C-reactive protein levels in patients with acute coronary syndrome
- 07/20 - Sedentary time as predictor of insulin resistance, independent of moderate or vigorous physical activity
- 07/16 - Abnormalities in carotid artery wall thickness and function in youth with obesity and type 2 diabetes
- 06/26 - Baseline leptin concentrations negatively correlated with weight loss degree in lifestyle interventions
- 06/23 - Metabolic syndrome associated with prostate cancer risk in African-American men
- 06/22 - Reduced forced vital capacity associated with incremental mortality in metabolic syndrome patients
- 06/19 - Direct association between obesity class and levels of inflammatory markers in a representative US population
- 06/17 - Dyslipidaemia is instrumental in the progression of diabetic neuropathy
- 06/15 - Fructose overconsumption leads to dyslipidaemia and ectopic lipid deposition
- 06/08 - Strong correlation between lipid depositions in the exocrine pancreas and metabolic syndrome
- 06/04 - The association between metabolic syndrome and either coronary artery disease or severity of peripheral arterial disease partly accounted for by low-grade systemic inflammation
- 05/26 - Triglyceride levels but not adipokine concentrations as metabolic determinants of advanced non-alcoholic fatty liver disease
- 05/18 - High prevalence of renal microvascular disease in patients with metabolic syndrome
- 05/15 - Visceral fat diameter as a major determinant of endothelial dysfunction in obese subjects
- 05/08 - Non-alcoholic fatty liver disease as risk factor for the development of diabetes and metabolic syndrome
- 05/06 - Visceral adipose tissue marginally more related to endothelium-dependent vasodilation than subcutaneous adiposity
- 04/30 - Hypothyroidism associated with metabolic syndrome in a cross-sectional study from South India
- 04/28 - The TG/HDL-C ratio as a powerful independent predictor of all-cause mortality and cardiovascular events
- 04/02 - Cardiovascular risk factors highly associated with erectile dysfunction in the Look AHEAD trial
- 03/30 - Weight loss shown to reverse blunted sympathetic responsiveness to glucose ingestion in insulin resistant metabolic syndrome patients
- 03/25 - Adipose tissue distribution as important determinant of systemic inflammation in type 2 diabetes
- 03/16 - Low serum high-density lipoprotein cholesterol as an independent predictor of gouty flares in patients with gouty arthropathy
- 03/10 - Pericardial fat and visceral abdominal fat independently associated with cardiovascular disease
- 03/06 - Significant increase in blood pressure nondipping in patients with metabolic syndrome and untreated hypertension
- 03/05 - Metabolic syndrome associated with a significant increase in incident aortic valve calcium
- 02/20 - Metabolic syndrome associated with increased risk of recurrence after catheter ablation of atrial fibrillation
- 02/19 - More pronounced effect of metabolic syndrome on resistance to intravenous thrombolysis for acute ischaemic stroke in women than in men
- 02/18 - Both diabetes and metabolic syndrome appear to be independently associated with higher osteoporosis prevalence
- 02/17 - Hepatocellular carcinoma associated with metabolic syndrome is often free of significant fibrosis
- 02/13 - Independent association between elevated concentrations of adiponectin and inducible ischaemia in stable coronary heart disease
- 01/27 - Impaired endothelial function as a common denominator of microvascular complications and atherosclerosis in type 2 diabetes
- 01/21 - Positive relationship between metabolic syndrome and depression, but not anxiety, in male Japanese workers
- 01/15 - Metabolic syndrome associated with lower heart rate variability in middle-aged male twins
- 01/13 - Visceral fat accumulation and low plasma adiponectin levels as promoters of colorectal carcinogenesis
- 01/12 - Nutritive skin microcirculatory dysfunction detected in normoglycaemic subjects with metabolic syndrome
- 01/05 - Elevated urinary albumin excretion as risk factor for diabetes mellitus in men
2008
- 12/30 - Strong correlation between plasma endocannabinoid levels and high plasma triacylglycerol and low HDL(3)-cholesterol in viscerally obese men
- 12/23 - Differences in cardiovascular risk factors among youths with type 2 diabetes and nondiabetic controls
- 12/09 - Insights into the systemic processes influencing arteriolar and venular calibre
- 12/05 - Metabolic syndrome linked to cataract formation in the Blue Mountains Eye Study
- 12/04 - Traditional risk factors for coronary heart disease shown to have an impact on vascular function in young people
- 12/01 - Depression as an important comorbidity of metabolic syndrome in a general population
- 11/26 - Metabolic syndrome as an independent risk factor of liver cirrhosis in patients with chronic hepatitis B
- 11/17 - PCOS associated with increased incidence of glucose intolerance and increased PAI-1 in overweight and obese adolescents
- 11/12 - ApoA5 genetic variants as robust genetic biomarkers of various clinical hyperlipoproteinaemia phenotypes linked by hypertriglyceridaemia
- 11/11 - Lower fat oxidation in black girls during puberty as a potential risk factor predisposing to obesity
- 11/04 - High concentrations of small dense low-density lipoprotein as highly specific markers of familial combined hyperlipidaemia
- 11/03 - Sleep-disordered breathing in adolescents with metabolic syndrome associated with increased sympathetic nervous system activity and leptin levels
- 10/30 - Metabolic syndrome associated with higher prevalences of left ventricular (LV) hypertrophy and left atrial dilation and with a reduction of LV function in the young
- 10/28 - Associations of coronary heart disease risk factors with arterial tissue lipids in young subjects
- 10/23 - Metabolically unfavourable body composition leading to increased risk of metabolic and cardiovascular diseases in psychotic patients
- 10/16 - No association found between genetic variants associated with insulin resistance and metabolic syndrome in young Asian Indians presenting with myocardial infarction
- 10/13 - Independent association of insulin and 24-h urinary noradrenaline with metabolic syndrome
- 10/07 - Resistin shown to be more strongly associated with inflammatory and fibrinolytic markers than with obesity and insulin resistance
- 10/03 - Metabolically benign obesity: its identification and characterization
- 09/26 - Apolipoprotein CIII as a crucial link between dyslipidaemia and insulin resistance
- 09/25 - The incidence of metabolic syndrome increases with progression through menopause as testosterone progressively dominates the hormonal milieu
- 09/23 - Severe periodontitis associated with metabolic syndrome in middle-aged subjects
- 09/23 - Severe periodontitis associated with metabolic syndrome in middle-aged subjects
- 09/17 - Endothelial function significantly associated with cardiovascular risk in women with sedentary occupations
- 09/15 - Contribution of chronic obstructive pulmonary disease to the obesity paradox in patients with peripheral artery disease
- 09/11 - Increased prevalence of metabolic syndrome in polycystic ovary syndrome
- 09/03 - Metabolic syndrome associated with marked increase of new onset diabetes, hypertension and left ventricular hypertrophy within the general population
- 09/02 - Visceral fat directly associated with liver inflammation and fibrosis independently of insulin resistance and hepatic steatosis
- 08/29 - Excess cardiovascular risk factors such as obesity and metabolic syndrome in patients with bipolar disorder
- 08/28 - Metabolic syndrome shown to play a crucial role in the development of recurrent ischaemic stroke
- 08/25 - Obesity-associated genetic variation within the FTO gene likely to be associated with diminished satiety
- 08/21 - Metabolic Syndrome traits associated with a self-reported history of kidney stones
- 08/20 - Metabolic syndrome features other than hyperglycaemia shown to increase neuropathic risk
- 08/15 - High prevalence of metabolic syndrome in chronic hepatitis C virus infection associated with a lack of sustained virologic response
- 08/13 - Impaired glycaemic profile during pregnancy as a risk factor for important metabolic abnormalities and adverse perinatal outcomes
- 08/06 - Accumulated daily physical activity as a major predictor of insulin sensitivity
- 07/31 - Polycystic ovary syndrome aggravates impairment of insulin sensitivity in obese but not in normal-weight women
- 07/29 - Nonalcoholic fatty liver disease strongly associated with multiple cardiovascular risk factors in overweight and obese children
- 07/25 - Adipose tissue inflammation possibly linked to vascular injury and increased cardiovascular risk in obese subjects
- 07/17 - No relationship between metabolic syndrome and arterial variables in obese children
- 06/26 - A sex hormone alteration may underlie visceral fat accumulation and thus ultimately metabolic syndrome
- 06/23 - Lower sex hormone-binding globulin more strongly associated with metabolic syndrome than lower testosterone in older men
- 06/17 - Interacting genetic risk factors and smoking influence on metabolic disturbances in schizophrenic patients
- 06/13 - Metabolic syndrome may be relevant to the continuum of metaplasia observed in patients presenting with Barrett’s oesophagus
- 06/12 - Variants in the fat mass and obesity associated (FTO) gene linked with polycystic ovary syndrome
- 06/11 - Inflammatory markers and albuminuria as independent predictors of incident heart failure
- 06/10 - Accumulation of intra-abdominal adiposity during adolescence promotes development of metabolic syndrome in both sexes but influences blood pressure adversely only in males
- 06/06 - Non-HDL cholesterol strongly associated with coronary artery calcification
- 06/05 - Higher visceral adipose tissue associated with higher VLDL and LDL particle number, larger VLDL particles and smaller LDL and HDL particles in type 2 diabetes
- 05/26 - Intra-abdominal fat may be a key determinant in the development of larger aortic diameters
- 05/20 - Obesity only weakly related to traditional cardiovascular risk factors in black South African women
- 05/19 - Inverse association of 25-hydroxyvitamin D and positive association of parathyroid hormone levels with metabolic syndrome among US adults
- 05/09 - Metabolic syndrome factors as important accelerators for type 2 diabetes in the Anglo-Celtic but not in the Chinese population
- 05/02 - Metabolic syndrome independently associated with the presence and extent of coronary atherosclerotic plaques
- 04/16 - The term metabolic syndrome does not adequately describe the effects of GnRH agonists in men with prostate cancer
- 03/26 - Proliferative diabetic retinopathy significantly associated with coronary atherosclerosis in the Veterans Affairs Diabetes Trial (VADT)
- 03/14 - Metabolic syndrome strongly associated with lacunar infection in middle-aged subjects
- 03/06 - The measurement of dysfunctional HDL may play an important role in coronary artery disease risk
- 02/21 - Seasonal changes in mood and behaviour linked to metabolic syndrome
- 02/19 - Cardiovascular risk factors are common in patients with young-onset diabetes regardless of autoimmunity status
- 02/14 - Diabetic retinopathy associated with an increased incidence of cardiovascular events in patients with type 2 diabetes
- 02/06 - Subpopulation of triglyceride-rich lipoproteins and HDL lipoproteins as better predictors of coronary heart disease than triglycerides and HDL-cholesterol concentrations in postmeniopausal women
- 01/23 - Retinal arteriolar narrowing shown to predict incident diabetes
- 01/17 - Larger retinal vascular calibre in subjects with diabetes
2007
- 12/24 - Substantial progression to metabolic syndrome after initiation of antiretroviral therapy in HIV infection
- 12/21 - High-molecular weight adiponectin as a better marker of the extent of coronary atherosclerosis than total adiponectin
- 12/19 - Possible association found between psoriasis and metabolic syndrome
- 12/11 - Telomere shortening of endothelial progenitor cells via increased DNA damage may play an important role in the pathogenesis of coronary artery disease
- 11/16 - Physical inactivity associated with insulin resistance and microvascular dysfunction in healthy volunteers
- 11/01 - Retinopathy signs independently associated with coronary artery calcification
- 10/31 - Diabetes associated with larger retinal arteriolar calibre and retinopathy with larger retinal venular calibre
- 10/15 - High prevalence of metabolic syndrome in patients with obstructive sleep apnoea
- 10/12 - Lipid overstorage in human cardiac myocytes as an early manifestation of impaired glucose tolerance and type 2 diabetes
- 10/11 - No relationship between metabolic syndrome and bone mineral density in a population-based US study
- 10/08 - Characteristics of body fat distribution and their relationships to insulin resistance in South Asian men compared to Caucasian men
- 09/21 - Variation in traits related to obesity, glucose metabolism and dyslipidaemia is mainly explained by genetic factors
- 09/14 - Clock genes shown to be associated with human metabolic syndrome
- 09/04 - Mild elevations of urine albumin excretion associated with atherogenic lipoprotein abnormalities in the Multi-Ethnic Study of Atherosclerosis
- 08/31 - Subjects with metabolic syndrome shown to have greater endothelial dysfunction than those without metabolic syndrome
- 08/09 - Elevation of liver enzymes and hepatic insulin resistance occur in the early stages of insulin resistance
- 08/08 - Impaired subcutaneous adipocyte lipogenesis associated with systemic insulin resistance and increased apolipoprotein B/AI ratio in both genders
- 08/03 - Higher frequency of cardiovascular damage in hypertensive patients with metabolic syndrome compared to those without metabolic syndrome
- 07/24 - Hyperglycaemia as main contributor of the association of metabolic syndrome with cognition
- 07/12 - Obesity and dieting associated with opposite changes in white matter expansion in humans
- Circulating adipokine levels primarily attributable to ponderal index in obese children - (04/07/2007)
- Interaction of sleep-disordered breathing and metabolic abnormalities in overweight and obese children and adolescents - (03/07/2007)
- Serum uric acid linked to risk factors of metabolic syndrome except for blood glucose - (02/07/2007)
- Higher indexes of insulin resistance and glucose intolerance in young adults with very low birth weight - (29/06/2007)
- Adipose tissue arachidonic acid as an independent marker of metabolic dysregulation in Costa Rican adults - (27/06/2007)
- Metabolic syndrome shown to produce clinically significant coronary atherosclerosis stenosis by a mechanism independent of an increase in arterial stiffness - (26/06/2007)
- Microvascular vasodilator function is impaired in obese patients, with little further impairment in impaired fasting glucose and type 2 diabetes patients - (22/06/2007)
- Circulating adiponectin levels shown to be a useful predictor of coronary endothelial function - (19/06/2007)
- Insulin resistance linked to the components of the metabolic syndrome in Black and White youth, and to biomarkers of endothelial function in White youth - (15/06/2007)
- Obstructive sleep apnoea associated with insulin resistance, inflammation and metabolic syndrome independently of body mass index - (12/06/2007)
- Plasma cytokines as independent predictors of atherosclerosis in humans - (01/06/2007)
- Midlife measures of central obesity and of hypertension linked to cognitive decline with age - (28/05/2007)
- Magnitude of risk factors for type 2 diabetes and cardiovascular disease varies markedly in moderately obese subjects - (24/05/07)
- Metabolic endotoxaemia triggers body weight gain and diabetes in mice - (16/05/07)
- Circulating levels of endothelial adhesion molecules linked to the risk of developing type 2 diabetes - (14/05/07)
- Untreated masked hypertensive subjects detected by home blood pressure measurement at increased risk for subclinical arterial damage - (10/05/07)
- Glomerular hyperfiltration associated with high metabolic risk - (04/05/07)
- Impaired fasting glucose as a metabolic marker of impaired cognitive function in the elderly - (27/04/07)
- Changes in weight associated with parallel changes in albuminuria in a population-based longitudinal study - (25/04/07)
- Reduced plasma natriuretic peptide levels as a manifestation of the metabolic syndrome - (17/04/07)
- Metabolic syndrome associated with increased risk of venous thromboembolism - (13/04/07)
- Target organ changes in essential hypertensive patients amplified by the metabolic syndrome across age groups - (10/04/07)
- Progressive metabolic derangement of glucose tolerance first detected during pregnancy mimics the pathogenesis of type 2 diabetes - (06/04/07)
- Impaired substrate switching and reduced muscle mitochondrial content in subjects with a family history of type 2 diabetes - (05/04/07)
- Acquired obesity associated with changes in lipid metabolism independent of genetic effects - (27/03/07)
- Chronic work stress linked to general and central obesity - (21/02/07)
- Dietary energy density as an independent predictor of obesity, elevated fasting insulin, and metabolic syndrome in US adults - (20/02/07)
- C-reactive protein as an "intermediate phenotype" for inflammation - (04/02/07)
- Fat cell enlargement as an independent marker of insulin resistance in non-diabetic subjects - (03/02/07)
- Metabolic syndrome shown to enhance sympathetic activation in congestive heart failure - (01/02/07)
- Metabolic syndrome as independent risk factor for erectile dysfunction in a large cohort study - (31/01/07)
2006
- Historical analysis of PAI-1 from its discovery to its potential role in cell motility and disease
- Changes in body shape, fat distribution with increasing parity
- Mutations of the ghrelin gene in people with the metabolic syndrome
- Ghrelin levels influenced by lifestyle factors
- Mechanism of triglyceride lowering in mice expressing human apolipoprotein A5
- Insulin secretion in hyperlipoproteinemias
- Simple fasting state measures to assess the progression from normal glucose tolerance to impaired glucose tolerance and to type 2 diabetes - (08/11/06)
- Plasma adiponectin levels inversely related to coronary artery disease severity but not to hypertension in nondiabetic patients - (06/11/06)
- Specific pharmacologic interventions are required for reducing metabolic syndrome risk - (31/10/06)
- High prevalence of postchallenge hyperglycaemia in non-alcoholic fatty liver disease patients - (30/10/06)
- Characterization of lipid phenotypes in children for the prevention of coronary heart disease - (17/10/06)
- The cat as a model for studying human obesity and diabetes - (10/10/06)
- Increased plasma leptin levels associated with insulin resistance (IR), inflammatory and haemostatic risk factors for cardiovascular disease (CVD) - (28/06/06)
- Novel mechanism of heart disease: myocardial steatosis - (04/05/06)
2005
2004
- Expression of adiponectin receptors in human macrophages and regulation by agonists of the nuclear receptors PPARalpha, PPARgamma, and LXR
- Mosaic analysis of insulin receptor function
- PPARs and the complex journey to obesity
- The Role of TNF-alpha in Insulin Resistance
- Adipose tissue, insulin action and vascular disease: inflammatory signals
- Low adipocyte-derived plasma protein adiponectin concentrations are associated with the metabolic syndrome and small dense low-density lipoprotein particles: atherosclerosis and insulin resistance study
- What is the Relationship Between Exercise and Metabolic Abnormalities? : A Review of the Metabolic Syndrome
- Obesity is the major determinant of elevated C-reactive protein in subjects with the metabolic syndrome
- Metabolic syndrome, inflammation, and exercise
- Relationship between C-reactive protein and visceral adipose tissue in healthy Japanese subjects
- Hypertension, insulin resistance, and the metabolic syndrome
- Adiponectin, inflammation, and the expression of the metabolic syndrome in obese individuals: the impact of rapid weight loss through caloric restriction
- Adiponectin and metabolic syndrome
