Increased risk of metabolic syndrome in women with prior gestational diabetes - 06/2005

The prevalence of the metabolic syndrome in a Danish population of women with previous GDM is 3-fold higher than in the general population

Compared with a control group of 1000 age-matched women, 481 Danish women (median age: 43 years) with a history of diet-treated gestational diabetes mellitus (GDM) had a three times higher prevalence of the metabolic syndrome after a median follow-up of 9.8 years following pregnancy. This result was independent of the criteria used to detect the metabolic syndrome (WHO, ATP III or EGIR). A more than 7-fold increased prevalence of the metabolic syndrome (by WHO criteria) was seen in obese women (BMI >30 kg/m2) with previous GDM.

Themes : Metabolic Syndrome and Diabetes (Including Glucose-Insulin Homeostasis)

Author(s) :
Lauenborg J, Mathiesen E, Hansen T, Glumer C, Jorgensen T, Borch-Johnsen K, Hornnes P, Pedersen O, Damm P.

Reference :
J Clin Endocrinol Metab 2005 Apr 19; [Epub ahead of print]

Pubmed reference :
PMID: 15840755