Overweight, obesity, hypertension and abnormal triglycerides highly associated with higher prevalence of hyperuricaemia in the Shandong coastal cities of Eastern China
Document Actions
Hyperuricaemia is associated with the metabolic syndrome phenotype, and is also a risk factor for atherosclerotic cardiovascular disease. Data from 5003 subjects randomly recruited from 5 coastal cities of Shandong province in Eastern China were collected in order to demonstrate the prevalence of hyperuricaemia and gout associated with dietary and lifestyle changes and to evaluate the implication of overweight, hypertension and abnormal triglycerides to the development of hyperuricaemia. In this population, the prevalence of hyperuricaemia was 13% and that of gout 1%, prevalences being significantly higher in men than in women. Compared to previous published data, a significant steady increase in the prevalence of hyperuricaemia was noted, the prevalence being much higher among urban residents compared to rural residents, and in developed cities compared to less developed ones. Furthermore, alcohol, overweight/obesity, hypertension and elevated triglycerides were highly associated with higher hyperuricaemia prevalence rates. These discrepancies were highly correlated with surrogate markers of affluence from socioeconomic development as shown by the increase of daily consumption of meat and seafood. Based on these findings, the authors conclude that there was a remarkable increase in the prevalence of hyperuricaemia and gout, which was highly associated with overweight, hypertension and abnormal triglycerides in the study population. In the authors’ view, these changes were highly correlated with markers of socioeconomic affluence, expressed as dietary and lifestyle changes.
Abstract
