Uncontrolled blood pressure associated with increased risk of incident diabetes
Document Actions
2009-march-23
As there is no information on whether incident diabetes is predicted by blood pressure (BP) control, the hazard of diabetes in relation to BP control was evaluated in 1754 nondiabetic, otherwise healthy, treated hypertensive patients. Criteria for uncontrolled BP were systolic blood pressure ≥140 mmHg and/or diastolic blood pressure ≥90 mmHg at last outpatient visit. Uncontrolled BP despite antihypertensive treatment was frequent (41%). Over the 3.4±1 year follow-up period, 109 subjects developed diabetes. After adjusting for confounding factors, Cox regression analysis revealed that uncontrolled BP significantly doubled the risk of incident diabetes, independently of the otherwise significant effects of age and baseline fasting glucose.
Abstract
