Low high-density lipoprotein cholesterol independently associated with presence of cardiovascular disease in Spanish hypertensive women
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The cross-sectional study aimed to determine the prevalence of low high-density lipoprotein cholesterol (HDL-C) and its relationship with cardiovascular disease (CVD) in 11,042 hypertensive Spanish women aged ≥55 years. In this patient population, the prevalence of a low HDL-C level (defined in this study as <46 mg/dL) was 24.3%, and was higher in women with diabetes or CVD. A low HDL-C was independently associated with excess weight, smoking, diabetes and presence of CVD, and inversely with age. After adjusting for other risk factors, there was an independent inverse association between HDL-C and the prevalence of CVD. In conclusion, one-fourth of the hypertensive Spanish women studied presented with low a HDL-C level, which was independently associated with the presence of CVD.
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