ADIPONECTIN

  • Update on therapeutic strategies to increase adiponectin function and secretion in metabolic syndrome.
    (Montecucco F, et al. Diabetes Obes Metab. 2009 May;11(5):445-54. Epub 2009 Feb 10.)
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  • The association between pulse wave velocity and metabolic syndrome and adiponectin in patients with impaired fasting glucose: cardiovascular risks and adiponectin in IFG.
    (Nam JS, et al. Diabetes Res Clin Pract. 2009 May;84(2):145-51. Epub 2009 Mar 3.)
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  • Effects of bisphenol A on adipokine release from human adipose tissue: Implications for the metabolic syndrome.
    (Ben-Jonathan N, et al. Mol Cell Endocrinol. 2009 May 25;304(1-2):49-54. Epub 2009 Mar 9.)
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BIOMARKERS

  • Increased circulating levels of matrix metalloproteinase (MMP)-8, MMP-9, and pro-inflammatory markers in patients with metabolic syndrome.
    (Gonçalves FM, et al. Clin Chim Acta. 2009 May;403(1-2):173-7. Epub 2009 Feb 28.)
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CANCER

  • Racial differences in risk of prostate cancer associated with metabolic syndrome.
    (Beebe-Dimmer JL, et al. Urology. 2009 May 9. [Epub ahead of print])
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  • Association of metabolic syndrome with insulin-like growth factors among adults in the US.
    (Saydah S, et al. Cancer Causes Control. 2009 May 5. [Epub ahead of print])
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CARDIOVASCULAR DISEASE

  • Metabolic syndrome and all-cause and cardiovascular disease mortality.
    (Saito I, et al. Circ J. 2009 May;73(5):878-84. Epub 2009 Mar 12.)
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  • Metabolic syndrome and carotid intima media thickness in the Health 2000 Survey.
    (Sipilä K, et al. Atherosclerosis. 2009 May;204(1):276-81. Epub 2008 Sep 4.)
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  • Myocardial lipid accumulation in patients with pressure-overloaded heart and metabolic syndrome.
    (Marfella R, et al. J Lipid Res. 2009 May 24. [Epub ahead of print])
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  • Metabolic syndrome: A predictor of adverse outcomes after carotid revascularization.
    (Protack CD, et al. J Vasc Surg. 2009 May;49(5):1172-80.e1; discussion 1180.)
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  • Circulating IL-8 levels in heart failure patients with and without metabolic syndrome.
    (Shin MJ, et al. Clin Chim Acta. 2009 Jul;405(1-2):139-42. Epub 2009 May 3.)
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DEFINING THE METABOLIC SYNDROME

  • A comprehensive definition for metabolic syndrome.
    (Huang PL. Dis Model Mech. 2009 May-Jun;2(5-6):231-7.)
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  • Use of confirmatory factor analysis for the identification of new components of the metabolic syndrome: the role of plasminogen activator inhibitor-1 and Haemoglobin A1c.
    (Boronat M, et al. Nutr Metab Cardiovasc Dis. 2009 May;19(4):271-6. Epub 2008 Sep 21.)
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  • The metabolic syndrome (MS) in the elderly: considerations on the diagnostic criteria of the International Diabetes Federation (IDF) and some proposed modifications.
    (Motta M, et al. Arch Gerontol Geriatr. 2009 May-Jun;48(3):380-4. Epub 2008 May 1.)
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DIABETES

  • Associations between components of the metabolic syndrome versus bone mineral density and vertebral fractures in patients with type 2 diabetes.
    (Yamaguchi T, et al. Bone. 2009 May 13. [Epub ahead of print])
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  • Overweight and the metabolic syndrome in adult offspring of women with diet-treated gestational diabetes mellitus or type 1 diabetes.
    (Clausen TD, et al. J Clin Endocrinol Metab. 2009 May 5. [Epub ahead of print])
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  • Metabolic syndrome is independently associated with microalbuminuria in type 2 diabetes.
    (Esteghamati A, et al. Acta Diabetol. 2009 May 29. [Epub ahead of print])
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  • Phosphodiesterase 5 inhibition improves beta-cell function in metabolic syndrome.
    (Hill KD, et al. Diabetes Care. 2009 May;32(5):857-9. Epub 2009 Feb 5.)
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  • C-peptide and chronic complications in patients with type-2 diabetes and the metabolic syndrome.
    (Mavrakanas T, et al. Presse Med. 2009 May 4. [Epub ahead of print])
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  • Association of FVC and total mortality in US adults with metabolic syndrome and diabetes.
    (Lee HM, et al. Chest. 2009 May 8. [Epub ahead of print])
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DIET, NUTRITION, AND METABOLISM
  • Protective effects of ethanolic extract of Zingiber officinale rhizome on the development of metabolic syndrome in high-fat diet-fed rats.
    (Nammi S, et al. Basic Clin Pharmacol Toxicol. 2009 May;104(5):366-73.)
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  • Dietary carotenoid intake is associated with lower prevalence of metabolic syndrome in middle-aged and elderly men.
    (Sluijs I, et al. J Nutr. 2009 May;139(5):987-92. Epub 2009 Mar 25.)
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  • Beneficial effect of food substitute containing L-arginine, omega-3 poly unsaturated fatty acid, and ribonucleic acid in preventing or improving metabolic syndrome: A study in 15 overweight patients and a study of fatty acid metabolism in animals.
    (Watanabe K, et al. J Clin Biochem Nutr. 2009 May;44(3):266-74. Epub 2009 Apr 25.)
    View Abstract
  • Relationship between n-3 and n-6 plasma fatty acid levels and insulin resistance in coronary patients with and without metabolic syndrome.
    (Nigam A, et al. Nutr Metab Cardiovasc Dis. 2009 May;19(4):264-70. Epub 2008 Sep 20.)
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  • A traditional rice and beans pattern is associated with metabolic syndrome in Puerto Rican older adults.
    (Noel SE, et al. J Nutr. 2009 May 20. [Epub ahead of print])
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  • Refined grain consumption and the metabolic syndrome in urban Asian Indians (Chennai Urban Rural Epidemiology Study 57).
    (Radhika G, et al. Metabolism. 2009 May;58(5):675-81.)
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  • Catabolism of lipoproteins and metabolic syndrome.
    (Therond P. Curr Opin Clin Nutr Metab Care. 2009 May 25. [Epub ahead of print])
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  • Effects of three different doses of a fruit extract of Terminalia chebula on metabolic components of metabolic syndrome, in a rat model.
    (Singh I, et al. Phytother Res. 2009 May 28. [Epub ahead of print])
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  • Central role of ceramide biosynthesis in body weight regulation, energy metabolism and the metabolic syndrome.
    (Yang G Dr, et al. Am J Physiol Endocrinol Metab. 2009 May 12. [Epub ahead of print])
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DRUG THERAPY

  • AMPK: an emerging drug target for diabetes and the metabolic syndrome.
    (Zhang BB, et al. Cell Metab. 2009 May;9(5):407-16.)
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  • Effects of fenofibrate treatment on prothrombotic state in patients with metabolic syndrome in relation to smoking and diabetes.
    (Jastrzebska M, et al. Med Sci Monit. 2009 May;15(5):PI27-33.)
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  • Effects of combined olmesartan and pravastatin on glucose intolerance and cardiovascular remodeling in a metabolic-syndrome model.
    (Mizukawa M, et al. Hypertens Res. 2009 May 22. [Epub ahead of print])
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EPIDEMIOLOGY

  • Metabolic syndrome as a predictor of cardiovascular diseases and type 2 diabetes in Koreans.
    (Hwang YC, et al. Int J Cardiol. 2009 May 29;134(3):313-21. Epub 2009 Jan 8.)
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  • Weight change and incident metabolic syndrome in Iranian men and women; a 3 year follow-up study.
    (Zabetian A, et al. BMC Public Health. 2009 May 13;9(1):138. [Epub ahead of print])
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  • Familial aggregation of the metabolic syndrome: Tehran Lipid and Glucose Study.
    (Azizi F, et al. Ann Nutr Metab. 2009 May 6;54(3):189-196. [Epub ahead of print])
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  • Could mitochondrial efficiency explain the susceptibility to adiposity, metabolic syndrome, diabetes and cardiovascular diseases in South Asian populations?
    (Bhopal RS, et al. Int J Epidemiol. 2009 May 7. [Epub ahead of print])
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  • Chemerin is associated with metabolic syndrome phenotypes in a Mexican American Population.
    (Bozaoglu K, et al. J Clin Endocrinol Metab. 2009 May 26. [Epub ahead of print])
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  • Relationship between two indicators of coronary risk estimated by the Framingham Risk Score and the number of metabolic syndrome components in Japanese male manufacturing workers.
    (Kawada T, et al. Metab Syndr Relat Disord. 2009 May 18. [Epub ahead of print])
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  • Impact of metabolic syndrome on elevated serum alanine aminotransferase levels in the Japanese population.
    (Saito T, et al. Metabolism. 2009 May 1. [Epub ahead of print])
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  • Prevalence of metabolic syndrome and factors associated with its components in Chinese adults.
    (Zuo H, et al. Metabolism. 2009 May 28. [Epub ahead of print])
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  • Of the three classifications of healthy lifestyle habits, which one is the most closely associated with the prevention of metabolic syndrome in Japanese?
    (Wada T, et al. Intern Med. 2009;48(9):647-55. Epub 2009 May 1.)
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  • Metabolic syndrome in a workplace: Prevalence, co-morbidities, and economic impact.
    (Schultz AB, et al. Metab Syndr Relat Disord. 2009 May 18. [Epub ahead of print])
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EXERCISE

  • Exercise training-induced changes in heart rate recovery in obese men with metabolic syndrome.
    (Kim MK, et al. Metab Syndr Relat Disord. 2009 May 18. [Epub ahead of print])
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GENETICS
  • Genetic variants at the PDZ-interacting domain of the scavenger receptor class B type I interact with diet to influence the risk of metabolic syndrome in obese men and women.
    (Junyent M, et al. J Nutr. 2009 May;139(5):842-8. Epub 2009 Mar 25.)
    View Abstract
  • Association between angiopoietin-like 6 (ANGPTL6) gene polymorphisms and metabolic syndrome-related phenotypes in the French MONICA Study.
    (Legry V, et al. Diabetes Metab. 2009 May 14. [Epub ahead of print])
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  • Resistin gene variation is associated with systemic inflammation but not plasma adipokine levels, metabolic syndrome or coronary atherosclerosis in nondiabetic Caucasians.
    (Qasim AN, et al. Clin Endocrinol (Oxf). 2009 May;70(5):698-705. Epub 2008 Aug 15.)
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  • The pathogenetic role of cortisol in the metabolic syndrome: a hypothesis.
    (Anagnostis P, et al. J Clin Endocrinol Metab. 2009 May 26. [Epub ahead of print])
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HYPERTENSION
  • A novel locus for arterial hypertension on chromosome 1p36 maps to a metabolic syndrome trait cluster in the Sorbs, a Slavic population isolate in Germany.
    (Hoffmann K, et al. J Hypertens. 2009 May;27(5):983-90.)
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  • The adverse prognostic significance of the metabolic syndrome with and without hypertension in patients who underwent complete coronary revascularization.
    (Kasai T, et al. J Hypertens. 2009 May;27(5):1017-24.)
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  • Metabolic syndrome in primary aldosteronism and essential hypertension: Relationship to adiponectin gene variants.
    (Ronconi V, et al. Nutr Metab Cardiovasc Dis. 2009 May 28. [Epub ahead of print])
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INNOVATIVE TECHNIQUES / MODELING

  • Connecting lipid droplet biology and the metabolic syndrome.
    (Le Lay S, et al. Prog Lipid Res. 2009 May-Jul;48(3-4):191-5. Epub 2009 Mar 20.)
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  • Towards application of rule learning to the meta-analysis of clinical data: An example of the metabolic syndrome.
    (Wojtusiak J, et al. Int J Med Inform. 2009 May 21. [Epub ahead of print])
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NON-ALCHOLIC FATTY LIVER DISEASE
  • Nonalcoholic fatty liver disease as a contributor to hypercoagulation and thrombophilia in the metabolic syndrome.
    (Targher G, et al. Semin Thromb Hemost. 2009 Apr;35(3):277-87. Epub 2009 May 18.)
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  • The metabolic syndrome and nonalcoholic fatty liver disease in children.
    (Sundaram SS, et al. Curr Opin Pediatr. 2009 May 12. [Epub ahead of print])
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  • Improvement of the metabolic syndrome and of non-alcoholic liver steatosis upon treatment of hypogonadal elderly men with parenteral testosterone undecanoate.
    (Haider A, et al. Exp Clin Endocrinol Diabetes. 2009 May 26. [Epub ahead of print])
    View Abstract

METABOLIC SYNDROME IN MEN

  • Metabolic syndrome (MS) and erectile dysfunction (ED) among obese non diabetic subjects.
    (Gatti A, et al. J Endocrinol Invest. 2009 May 5. [Epub ahead of print])
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METABOLIC SYNDROME IN WOMEN

  • Loss of ovarian function in the VCD mouse-model of menopause leads to insulin resistance and a rapid progression into the metabolic syndrome.
    (Romero-Aleshire MJ, et al. Am J Physiol Regul Integr Comp Physiol. 2009 May 13. [Epub ahead of print])
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  • Metabolic syndrome and its associated risk factors in Brazilian postmenopausal women.
    (Petri Nahas EA, et al. Climacteric. 2009 May 2:1-8. [Epub ahead of print])
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  • Evaluating the association between all components of the metabolic syndrome and pre-eclampsia.
    (Srinivas SK, et al. J Matern Fetal Neonatal Med. 2009 May 25:1-9. [Epub ahead of print])
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MISCELLANEOUS

  • Metabolic syndrome and quality of life (QOL) using generalised and obesity-specific QOL scales.
    (Han JH, et al. Int J Clin Pract. 2009 May;63(5):735-41.)
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MODELING / INNOVATIVE TECHNIQUES

  • A unique rodent model of cardiometabolic risk associated with the metabolic syndrome and polycystic ovary syndrome.
    (Shi D, et al. Endocrinology. 2009 May 21. [Epub ahead of print])
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  • Association of serum leptin levels with homeostasis model assessment-estimated insulin resistance and metabolic syndrome: The key role of central obesity.
    (Esteghamati A, et al. Metab Syndr Relat Disord. 2009 May 6. [Epub ahead of print])
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  • Canonical transient receptor potential channels expression is elevated in a porcine model of metabolic syndrome.
    (Hu G, et al. Mol Endocrinol. 2009 May;23(5):689-99. Epub 2009 Feb 12.)
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OBESITY

  • Detailed description of early response of metabolic syndrome after laparoscopic Roux-en-Y gastric bypass.
    (Ali MR, et al. Surg Obes Relat Dis. 2009 May-Jun;5(3):346-51. Epub 2008 Nov 21.)
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  • Abdominal obesity is essential for the risk of venous thromboembolism in the metabolic syndrome: the Tromsø study.
    (Borch KH, et al. J Thromb Haemost. 2009 May;7(5):739-45. Epub 2008 Nov 24.)
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  • Basal serum prolactin levels in obesity-unrelated to parameters of the metabolic syndrome and unchanged after massive weight loss.
    (Ernst B, et al. Obes Surg. 2009 May 9. [Epub ahead of print])
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  • Impact of laparoscopic roux-en-Y gastric bypass on metabolic syndrome, inflammation, and insulin resistance in super versus morbidly obese women.
    (Iannelli A, et al. Obes Surg. 2009 May;19(5):577-82. Epub 2008 Nov 19.)
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  • Weight loss may reverse blunted sympathetic neural responsiveness to glucose ingestion in obese subjects with metabolic syndrome.
    (Straznicky NE, et al. Diabetes. 2009 May;58(5):1126-32. Epub 2009 Feb 2.)
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  • Sex-dependent associations of leptin with metabolic syndrome-related variables: The Stanislas Study.
    (Samara A, et al. Obesity (Silver Spring). 2009 May 14. [Epub ahead of print])
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  • Effect of weight loss on HDL-apoA-II kinetics in the metabolic syndrome.
    (Ng TW, et al. Clin Sci (Lond). 2009 May 21. [Epub ahead of print])
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OXIDATIVE STRESS

  • Oxidative stress and metabolic syndrome.
    (Roberts CK, et al. Life Sci. 2009 May 22;84(21-22):705-12. Epub 2009 Mar 9. Review.)
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  • Metabolic syndrome and oxidative stress.
    (Ando K, et al. Free Radic Biol Med. 2009 May 3. [Epub ahead of print])
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PEDIATRICS

  • Metabolic syndrome in obese adolescents.
    (Bustos P, et al. Pediatr Diabetes. 2009 May 19. [Epub ahead of print])
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  • Adolescent manifestations of metabolic syndrome among children born to women with gestational diabetes in a general-population birth cohort.
    (Vääräsmäki M, et al. Am J Epidemiol. 2009 May 15;169(10):1209-15. Epub 2009 Apr 10.)
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  • The association of elevated alanine aminotransferase and the metabolic syndrome in an overweight and obese pediatric population of multi-ethnic origin.
    (van Vliet M, et al. Eur J Pediatr. 2009 May;168(5):585-91. Epub 2008 Aug 12.)
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  • Prevalence of components of the metabolic syndrome in schoolchildren with newly diagnosed type 2 diabetes mellitus.
    (Urakami T, et al. Pediatr Diabetes. 2009 May 19. [Epub ahead of print])
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  • Prevalence of obesity and metabolic syndrome in Indigenous Australian youths.
    (Valery PC, et al. Obes Rev. 2009 May;10(3):255-61. Epub 2008 Dec 15.)
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  • Factor analysis of metabolic syndrome components in severely obese girls and boys.
    (Lafortuna CL, et al. J Endocrinol Invest. 2009 May 5. [Epub ahead of print])
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  • Impact of obesity on metabolic syndrome components and adipokines in prepubertal children.
    (Madeira IR, et al. J Pediatr (Rio J). 2009 May-Jun;85(3):261-8. Epub 2009 Feb 10.)
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PSYCHOLOGICAL DISORDERS

  • Association of adiponectin and metabolic syndrome among patients taking atypical antipsychotics for schizophrenia: A cohort study.
    (Bai YM, et al. Schizophr Res. 2009 Jun;111(1-3):1-8. Epub 2009 May 5.)
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  • Prevalence of metabolic syndrome among patients with schizophrenia or schizoaffective disorder in Taiwan.
    (Huang MC, et al. Acta Psychiatr Scand. 2009 May 7. [Epub ahead of print])
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  • Depressive symptoms and metabolic syndrome: Selective association in older women.
    (Laudisio A, et al. J Geriatr Psychiatry Neurol. 2009 May 7. [Epub ahead of print])
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RENAL DISORDERS / KIDNEY FUNCTION

  • Does metabolic syndrome have an impact on the quality of life and mood of hemodialysis patients?
    (Afsar B, et al. J Ren Nutr. 2009 May 21. [Epub ahead of print])
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  • Kidney pathological changes in metabolic syndrome: a cross-sectional study.
    (Alexander MP, et al. Am J Kidney Dis. 2009 May;53(5):751-9. Epub 2009 Apr 1.)
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  • Impact of metabolic syndrome and malnutrition on mortality in chronic hemodialysis patients.
    (Stolic RV, et al. J Ren Nutr. 2009 May 21. [Epub ahead of print])
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  • Metabolic syndrome and anthropometric factors in Japanese patients with chronic kidney disease.
    (Sawara Y, et al. Heart Vessels. 2009 May;24(3):199-203. Epub 2009 May 24.)
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RISK FACTORS

  • NPAS2 and PER2 are linked to risk factors of the metabolic syndrome.
    (Englund A, et al. J Circadian Rhythms. 2009 May 26;7(1):5. [Epub ahead of print])
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  • The metabolic syndrome and its traits as risk factors for subclinical atherosclerosis.
    (Holewijn S, et al. J Clin Endocrinol Metab. 2009 May 5. [Epub ahead of print])
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  • Metabolic syndrome and its components as risk factors for first-ever acute ischemic noncardioembolic stroke.
    (Maruyama K, et al. J Stroke Cerebrovasc Dis. 2009 May-Jun;18(3):173-7.)
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  • Multiparity and risk of metabolic syndrome: Isfahan Healthy Heart Program.
    (Mousavi E, et al. Metab Syndr Relat Disord. 2009 May 18. [Epub ahead of print])
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  • Metabolic syndrome and risk of venous thromboembolism: Longitudinal Investigation of Thromboembolism Etiology.
    (Steffen LM, et al. J Thromb Haemost. 2009 May;7(5):746-51. Epub 2009 Jan 19.)
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  • Metabolic syndrome as a risk factor for cardiovascular disease, mortality, and progression of diabetic nephropathy in type 1 diabetes.
    (Thorn LM, et al. Diabetes Care. 2009 May;32(5):950-2. Epub 2009 Feb 5.)
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  • Serum gamma-glutamyl transferase activity predicts future development of metabolic syndrome defined by 2 different criteria.
    (Jo SK, et al. Clin Chim Acta. 2009 May;403(1-2):234-40. Epub 2009 Mar 28.)
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  • Retinopathy in nondiabetic persons with the metabolic syndrome: findings from the Third National Health and Nutrition Examination Survey.
    (Keenan JD, et al. Am J Ophthalmol. 2009 May;147(5):934-44, 944.e1-2. Epub 2009 Feb 25.)
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  • Asthma-like symptoms are increased in the metabolic syndrome.
    (Lee EJ, et al. J Asthma. 2009 May;46(4):339-42.)
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  • Persistent rotating shift-work exposure accelerates development of metabolic syndrome among middle-aged female employees: a five-year follow-up.
    (Lin YC, et al. Chronobiol Int. 2009 May;26(4):740-55.)
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  • Endocannabinoids, FOXO and the metabolic syndrome: Redox, function and tipping point - The view from two systems.
    (Nunn AV, et al. Immunobiology. 2009 May 18. [Epub ahead of print])
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  • The metabolic syndrome: how it may influence hepatic stellate cell activation and hepatic fibrosis.
    (Lanthier N, et al. Curr Opin Clin Nutr Metab Care. 2009 May 26. [Epub ahead of print])
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SCREENING & TREATMENT
  • Longitudinal paths to the metabolic syndrome: can the incidence of the metabolic syndrome be predicted? The Baltimore Longitudinal Study of Aging.
    (Scuteri A, et al. J Gerontol A Biol Sci Med Sci. 2009 May;64(5):590-8. Epub 2009 Mar 6.)
    View Abstract

SLEEP DISORDERS

  • Empirical evidence for "syndrome Z": a hierarchical 5-factor model of the metabolic syndrome incorporating sleep disturbance measures.
    (Nock NL, et al. Sleep. 2009 May 1;32(5):615-22.)
    View Abstract

STROKE

  • Relationship between the metabolic syndrome and the incidence of stroke after complete coronary revascularization over a 10-year follow-up period.
    (Kasai T, et al. Atherosclerosis. 2009 May 3. [Epub ahead of print])
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Framingham Risk Assessment Tool
Estimates 10-year risk of developing hard CHD
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Procam Risk Calculator
Estimates your risk of a heart attack (myocardial infarction) within the next 10 years based upon data of the PROCAM Study
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SCORE
(European High Risk Chart)

Estimates 10 year risk of fatal CVD in high risk regions of Europe by gender, age, systolic blood pressure, total cholesterol and smoking status.
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UKPDS Risk Engine
The UKPDS Risk Engine is a type 2 diabetes specific risk calculator based on 53,000 patients years of data from the UK Prospective Diabetes Study, which also provides an approximate 'margin of error' for each estimate.
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Coordinated by Dr. Scott Grundy, Past-President of the IAS