Trial - ADDITION
(Anglo-Danish-Dutch Study of Intensive Treatment In People with Screen
Detected Diabetes in Primary Care )
Outcomes:
Cardiovascular mortality; cardiovascular morbidity; MI (non
fatal); stroke (non fatal); revascularization; amputations.
Expected Total Enrollment:
3000 subjects with no known diabetes mellitus.
Intervention:
Screening for type 2 diabetes and intensive treatment compared
to standard treatment (intensive ADDITION protocol: includes
structured lifestyle education, dietary modification,
increased physical activity, and smoking cessation, and
intensive treatment of blood glucose, blood pressure
and lipids, and prophylactic aspiring with or without
motivational interviewing, on mortality, macrovascular
and microvascular disease).
Study Design:
Randomized, open label, active control, factorial assignment.
Additional
Information
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